FEBS Practical Course

Advanced Imaging of molecular complexes in living cells

Molecular complexes play an important role in cellular processes like transcription, receptor signaling and cytoskeletal structure formation. Malfunction of the individual protein components and their interplay may result in disease. Microscopic techniques can be used to elucidate complex composition, organization and dynamics within the living cell.

This practical advanced course aims to provide young scientists in this field with theoretical background and to give hands-on experience of state-of-the-art microscopy techniques.

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The Federation of European Biochemical Societies (FEBS) has become one of Europe's largest organizations in the molecular life sciences, with over 36,000 members across more than 35 biochemistry and molecular biology societies (its 'Constituent Societies') in different countries of Europe and neighbouring regions. FEBS thereby provides a voice to a large part of the academic research and teaching community in Europe and beyond. As a charitable organization, FEBS promotes, encourages and supports biochemistry, molecular biology, cell biology, molecular biophysics and all related research areas in a variety of ways.

The van Leeuwenhoek Centre for Advanced Microscopy (LCAM) is a formal collaboration between three innovative microscopy centres at the Faculty of Science (FNWI) of the University of Amsterdam, the Academic Medical Centre (AMC) and the Netherlands Cancer Institute (NKI).

The formalized collaboration capitalizes on a large degree of synergy between the principle investigators in developing, adapting and applying advanced microscopy for use in cell biology. Besides delivering access to the diverse advanced microscopy instruments, LCAM has developed as a leading centre in functional live cell imaging (FRET, FLIM, FCCS, FCS, FRAP and spectral imaging).

LCAM has become a Euro-BioImaging Flaghship centre for Functional Imaging and High Content Microscopy.

The University of Amsterdam (UvA) has a rich history dating back to 1632, when its forerunner, the Golden Age school Athenaeum Illustre, was established.

Today, with some 30,000 students, 5,000 staff, more than 100 nationalities and a budget of more than 600 million euros, it is one of the largest comprehensive universities in Europe.

The UvA is a broad, research-intensive institution rooted in the history of Amsterdam, an internationally oriented academic community that can compete with leading universities in the Netherlands and around the world. The UvA provides academic training in all areas of science and scholarship, and welcomes students and staff – from all backgrounds, cultures and faiths – who wish to devote their talents to the development and transfer of academic knowledge as a rich cultural resource and foundation for sustainable progress.