The ability of cells to perceive and correctly respond to their environment is the basis of development, tissue repair and immunity as well as normal tissue homeostasis. The nucleus plays a central role in these processes because in this organelle the genetic blueprint of the cell is located and highly dynamic processes like gene activation, transcription and chromosome duplication are taking place.
By increasing the understanding of the complex nuclear organisation and signaling, related diseases can be treated more effectively. Microscopic techniques allow to visualize nuclear organisation and elucidate signaling complexes and their dynamics in time
This practical advanced course will provide participants the theoretical background and give hands-on experience of state-of-the-art microscopy techniques under guidance of experts in the field.